Giuseppe Pettinato, United States

Giuseppe Pettinato, Ph.D., is a molecular biologist with a doctorate in Embryology from the University of Catania, completed through a collaborative program with the Andalusian Center for Molecular Biology and Regenerative Medicine (CABIMER) in Seville, Spain. With over 20 years of experience in stem cell biology, organoid engineering, and translational medicine, he is currently an Instructor in Medicine at Harvard Medical School and the PI and Director of the Stem Cells and Organoids Research Engineering (SCORE) Center within the Division of Gastroenterology at Beth Israel Deaconess Medical Center.

Dr. Pettinato has developed innovative and scalable methodologies for generating human organoids from hiPSCs, including microfabricated microwell arrays that promote rapid and uniform organoid formation. His laboratory has established robust differentiation protocols for liver organoids and is extending this work to pancreas and intestinal systems. These platforms are being used to model complex human diseases, including NAFLD, NASH, ALD, HBV infection, type 1 diabetes, and inflammatory bowel diseases, providing powerful tools for mechanistic studies, drug discovery, and translational therapeutic development.